What is new in this update?
The first AAP neonatal guidance was provided on April 2, 2020, shortly after the onset of the global pandemic, when it was apparent that SARS-CoV-2 was very contagious and infected individuals could suffer severe mortality and morbidity. Since that time, published evidence as well as data provided to the National Registry for Surveillance and Epidemiology of Perinatal COVID-19 Infection has better informed the risks of perinatal disease, resulting in revisions to the guidance, most recently on May 4, 2021. In this current update posted on December 1, 2021, guidance on infection prevention measures for hospital personnel remains largely unchanged. We have updated statistics from the Perinatal COVID-19 Registry, and include published evidence on neonatal SARS-CoV-2. We anticipate additional revision to this guidance as further evidence becomes available to inform newborn management.