Postpartum pharmacologic thromboprophylaxis and complications in a US cohort Background Venous thromboembolism accounts for approximately 9% of pregnancy-related deaths in the United States. National guidelines recommend postpartum risk stratification and pharmacologic prophylaxis in…
Read More from AJOG: Postpartum pharmacologic thromboprophylaxis and complications in a US cohort
Society for Maternal-Fetal Medicine Special Statement: Prophylactic low-dose aspirin for preeclampsia prevention—quality metric and opportunities for quality improvement Prophylactic low-dose aspirin reduces the rates of preeclampsia, preterm birth, fetal growth…
Cost-effectiveness of induction of labor at 39 weeks vs expectant management by cervical examination Background Previous analyses have demonstrated the cost effectiveness of elective induction of labor at 39 weeks…
Postpartum navigation decreases severe maternal morbidity most among Black women Background Postpartum care is crucial for addressing conditions associated with severe maternal morbidity and mortality. Examination of programs that affect…
Examining recent trends in spontaneous and iatrogenic preterm birth across race and ethnicity in a large managed care population Background For the past several decades, epidemiological studies originating from the…
Optimizing the management of acute, prolonged decelerations and fetal bradycardia based on the understanding of fetal pathophysiology Any acute and profound reduction in fetal oxygenation increases the risk of anaerobic…
Special Issue – Labor and Delivery…
Criteria for placental examination for obstetrical and neonatal providers Pathologic examination of the placenta can provide insight into likely (and unlikely) causes of antepartum and intrapartum events, diagnoses with urgent…
Read More from AJOG: Criteria for placental examination for obstetrical and neonatal providers
OBJECTIVE Our objective was to determine whether large fibroids, particularly those exceeding 10 cm in size, are associated with postpartum hemorrhage (PPH). Currently, there is limited data on the relationship…
Read More from AJOG: Fibroid Size and Number and Risk of Postpartum Hemorrhage
AJOG: Low-Dose aspirin use in pregnancy and risk or preterm birth: a Swedish register-based cohort study Background Preterm birth is the leading cause of neonatal mortality and morbidity. Women who…
Alternative to intensive management of the active phase of the second stage of labor: a multicenter randomized trial (Phase Active du Second STade trial) among nulliparous women with an epidural…
Clinical Opinion: Toward the elimination of race-based medicine: replace race with racism as preeclampsia risk factor Pregnancy-related morbidity and mortality continue to disproportionately affect birthing people who identify as Black….
Effect of long-duration oxygen vs room air during labor on umbilical cord venous partial pressure of oxygen: a randomized controlled trial Background There are limited data to guide the duration…
Expert Review: Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes Cannabis is the most commonly used federally illegal drug in the United States and the world, especially among…
Fetal heart rate tracings associated with eclamptic seizures Background Although there is a well-known association between fetal bradycardia and maternal eclampsia, the characteristics of fetal heart rate tracings after…
Read More from AJOG: Fetal heart rate tracings associated with eclamptic seizures
Special Report: Racism and perinatal health inequities research: where we have been and where we should go For more than a century, substantial racial and ethnic inequities in perinatal health…
Maternal pregnancy outcomes in women with cardiomyopathy: a systematic review and meta-analysis Objective This study aimed to systematically assess the impact of cardiomyopathy on maternal pregnancy outcomes. Data Sources PubMed,…
Background Spontaneous preterm birth remains the main driver of childhood morbidity and mortality. Because of an incomplete understanding of the molecular pathways that result in spontaneous preterm birth, accurate predictive…
Read More from AJOG: Predictive RNA profiles for early and very early spontaneous preterm birth
Background Among nonpregnant individuals, diabetes mellitus and high body mass index increase the risk of COVID-19 and its severity. Objective This study aimed to determine whether diabetes mellitus and high…
Background Umbilical cord arterial and venous blood gas values reflect the acid-base balance status of a newborn at birth. Derangement in these values has been linked to poor neonatal outcomes…
Background Globally, the number of children born by cesarean delivery is constantly increasing. However, hormonal and physiological changes associated with labor and vaginal delivery are considered necessary for lung maturation….
Read More from AJOG: Are children born by cesarean delivery at higher risk for respiratory sequelae?
ABSTRACT Background The onset of the term human parturition involves myometrial gene expression changes to transform the uterus from a quiescent to a contractile phenotype. It is uncertain whether the…
ABSTRACT Background Antenatal depression affects approximately 1 of 7 pregnancies, with an increasing prevalence across gestation. Data regarding the associations between antenatal depression and adverse pregnancy outcomes yielded conflicting results….
Read More from AJOG: Trajectories of antenatal depression and adverse pregnancy outcomes
ABSTRACT Background The rate of cesarean delivery is continuously increasing with the leading indication being a previous cesarean delivery. For women with 1 previous cesarean delivery, it is generally agreed…
Read More from AJOG: Timing of cesarean delivery in women with ≥2 previous cesarean deliveries
ABSTRACT Background Determining fetal head descent, expressed as fetal head station and engagement is an essential part of monitoring progression in labor. Assessing fetal head station is based on the…
ABSTRACT Background The safest mode of delivery to use for very preterm infants is an ongoing topic of debate. There are many reasons to perform a cesarean delivery in cases…
Read More from AJOG: Neonatal morbidity and mortality by mode of delivery in very preterm neonates
ABSTRACT Background 17α-hydroxyprogesterone caproate is a synthetic progestogen initially approved in the 1950s to treat gynecologic and obstetrical conditions. Despite continued concerns about safety and short-term efficacy regarding the use…
ABSTRACT OBJECTIVE To examine the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and the risk of preeclampsia. DATA SOURCES MEDLINE, EMBASE, POPLINE, CINAHL, LILACS, and…
Visit the AJOG website for useful articles and videos on Preeclampsia/Eclampsia at https://www.ajog.org/preeclampsia…
Read More from AJOG releases supplemental resources on Preeclampsia/Eclampsia
Maternal tolerance of the semiallogenic fetus necessitates conciliation of competing interests. Viviparity evolved with a placenta to mediate the needs of the fetus and maternal adaptation to the demands of…