ABSTRACT
Pregnancy Mortality Surveillance System (PMSS) data from 2012–2022 were analyzed for this descriptive study. Specific subclassifications of deaths within the PMSS category of “other noncardiovascular medical conditions” (OMC) were analyzed by sociodemographic characteristics, and pregnancy-related mortality ratios (PRMRs; pregnancy-related deaths/100,000 live births) were calculated within each subclassification. Prepandemic (2012–2019) and coronavirus disease 2019 (COVID-19) pandemic (2020–2022) time periods are reported separately. The overall OMC-specific PRMR was 2.20 (95% CI, 2.06–2.35). Epilepsy was the most frequent specific subclassification of pregnancy-related OMC deaths before (15.7%) and during (16.1%) the COVID-19 pandemic. Diabetes (10.7%) and asthma (10.1%) followed epilepsy prepandemic, and asthma (13.1%) and diabetes (10.2%) followed during the pandemic. Reporting subclassifications of pregnancy-related deaths improves the ability to focus attention and interventions on these less frequently occurring consistent causes of pregnancy-related death.